Category: Reviews

Defending plasma T3 is a biological priority

Defending plasma T3 is a biological priority.

Sherine M. Abdalla and Antonio C. Bianco. Clinical Endocrinology (2014) in press Abstract Triiodothyronine (T3), the active form of thyroid hormone is produced predominantly outside the thyroid parenchyma secondary to peripheral tissue deiodination of...

Thyroid hormone deiodinases and cancer

Thyroid hormone deiodinases and cancer.

Casula S, Bianco AC. Front Endocrinol (Lausanne). 2012 Jun 1; 3: 74. Abstract Deiodinases constitute a group of thioredoxin fold-containing selenoenzymes that play an important function in thyroid hormone homeostasis and control of thyroid...

Cracking the metabolic code for thyroid hormone signaling

Cracking the metabolic code for thyroid hormone signaling.

Bianco AC. Endocrinology. 2011 Sep; 152(9): 3306-11. Abstract Cells are not passive bystanders in the process of hormonal signaling and instead can actively customize hormonal action. Thyroid hormone gains access to the intracellular environment...