A TRb-selective agonist confers resistance to diet-induced obesity.
Thyroid hormone receptor b (TRb also listed as THRB on the MGI Database)-selective agonists activate brown adipose tissue (BAT) thermogenesis, while only minimally affecting cardiac activity or lean body mass. Here, we tested the hypothesis that daily administration of the TRb agonist GC- 24 prevents the metabolic alterations associated with a hypercaloric diet. Rats were […]