Iodine Landmark Paper: Pituitary Nuclear 3,5,3 -Triiodothyronine and Thyrotropin Secretion: An Explanation for the Effect of Thyroxine.
Iodine is an essential component of thyroid hormones. The thyroglobulin-derived iodothyronine molecules contain 3 or 4 iodine atoms that are covalently bound during iodide organification. This process, also known as iodination, is catalyzed by thyroid peroxidase and requires that the thyroid cell concentrate iodide from plasma. Iodine is readily available from the ocean, and salt-water […]